The Kids Research Institute Australia has an opening for a postdoctoral position in paediatric cancer transcriptomics with a focus on brain tumours. The position, part of the newly established The Kids Cancer Centre and Personalised Medicine Centre for Children, aims to utilise bulk, single cell and spatial RNAseq data to discover new disease drivers and identify new therapeutic opportunities.
The postdoc will be involved in the analysis and interpretation of patient-derived tumour samples. In addition to the routine analysis of bulk RNAseq samples, our project involves single cell and spatial transcriptomics samples. These innovative approaches have the potential to map tumour heterogeneity at an unprecedented resolution and offer candidate applicants the unique opportunity to build their capacity in these emerging fields in cancer research. A strong focus will be on extracting potential biomarkers and signatures to be followed up by laboratory experiments. This work has the potential to lead to greater improvements in patient wellbeing, through a more targeted approach to clinical care.
The candidate will develop analysis pipelines to be uniformly applied to transcriptome data from two investigative streams:
- Paediatric brain tumours - understanding the heterogeneity of gene expression changes that occur in response to therapy, and in subsequent treatment-refractory disease
- Integration of whole genome sequencing and transcriptome profiling.
The position represents an exciting opportunity to work at the crossroads between basic science and clinical practice. The successful candidate will have the unique opportunity to be part of a truly inter-disciplinary team composed of molecular biologists, statisticians, computational biologists and clinicians.
The successful candidate should have:
- A PhD in a relevant subject area (e.g. Cancer, Genomics, Transcriptomics, Computational Biology, Bioinformatics, Computer Science, Statistics) and some background in programming and command line UNIX/ Linux
- Experience in cancer biology or related field is a bonus
- Excellent communication skills.
In addition all candidates should have at least two first author publications in reputed journals and demonstrated their ability to work well in a team. We expect all our lab members to be strongly self-motivated and ambitious.
This is a full time position fixed term for 2 years with the possibility of extension. Remuneration package includes access to generous salary packaging.
How to Apply:
Applicants should read the Job description available here.
Forward your CV along with a cover letter to applications@telethonkids.org.au.
Please quote the position title in the subject heading of your email application.
For further information about this position please contact Timo Lassmann.
Closing date: 5pm, Thursday December 7th, 2017