Paul Fournier, Tim Jones, Liz Davis
Study Staff: Wayne soon, Heather Roby; Ray Davey
There are no adequate guidelines to reduce glycaemic excursions associated with physical activity in individuals with type 1 diabetes. Current guidelines recommend an increase in carbohydrate (CHO) intake before, during and after exercise. Our own recent findings suggest that exercise-mediated glycaemic excursions can be minimised by engaging in intermittent high-intensity exercise rather than continuous moderate-intensity, and that, under these conditions, adhering to current CHO intake guidelines may increase the magnitude of glycaemic excursions. The overall aim of this study is the development and evaluation of recommendations for reducing glycaemic excursions with exercise.
AIM: This study will evaluate the effect of two types of aerobic exercise, under basal insulin conditions with or without CHO intake as per current hypoglycaemia prevention guidelines on blood glucose profiles during and immediately following exercise.
METHOD: 14 individuals with type 1 diabetes and without complications will be tested on four occasions during which they will perform 40 minutes of either continuous moderate-intensity exercise or intermittent high-intensity exercise on a stationery bicycle, with and without additional CHO as per ADA guidelines. Moderate intensity exercise will involve cycling at 55% VO2 peak for 40mins, while intermittent high intensity exercise will involve 40 mins repetitions of 1min moderate exercise and 4sec all out sprints, ending in a 10sec all out sprint.
Participants will be monitored for changes in blood glucose levels during and in the immediate post-exercise period. They will also be monitored for sensor glucose profiles during and in the 24hr following exercise.
Funder: Internal