Elizabeth Milne, Carol Bower, Nick de Klerk, Ursula Kees,
External collaborators:
Bruce Armstrong, Frank van Bockxmeer, Michelle Haber, Rodney Scott, John Attia, Murray Norris, Lin Fritschi, Margaret Miller, Judith Thompson, Frank Alvaro, Catherine Cole, Luciano Dalla Pozza, John Daubenton, Peter Downie, Marie Kirby, Liane Lockwood, Glenn Marshall, Elizabeth Smibert, Ram Suppiah
Researchers in the Childhood Cancer Epidemiology program have continued analysing data collected between 2003 and 2007 in this national case-control study of the risk factors for childhood acute lymphoblastic leukaemia (ALL).
The study recruited children with ALL and their parents from the nine paediatric oncology units nationwide, together with control children from around Australia. DNA samples were collected and parents were surveyed about a wide range of exposures.
Funders: NHMRC Grant #254539, and Cancer Council WA.
The following papers using data from this study were published in 2016:
- Hungate EA, et al., A variant at 9p21.3 functionally implicates CDKN2B in paediatric B-cell precursor acute lymphoblastic leukaemia aetiology. Nat Commun, 2016. 7: p. 10635.
- Bailey HD, Armstrong BK, Milne E, Schuz J, Clavel J. The associations between maternal factors during pregnancy and the risk of childhood acute lymphoblastic leukemia: a meta-analysis. Pediatric Blood and Cancer Pediatr Blood Cancer 2016;63(5):951-2.
The following papers using data from this study were published in 2015:
- Bailey HD, Metayer C, MilneE, et al. Home paint exposures and risk of childhood acute lymphoblastic leukemia: Findings from the Childhood Leukemia International Consortium. Cancer Causes and Control, 2015: 26(9);1257-1270
- Bailey HD, Infante-Rivard C, Metayer C, Clavel J, Lightfoot T, Kaatsch P, Roman E, Magnani C, Spector LG, Petridou E, MilneE et al. Home pesticide exposures and risk of childhood leukemia: Findings from the Childhood Leukemia International Consortium. International Journal of Cancer, 2015:137(11); 2644-2663
- Paltiel O, Tikellis G, Linet L, Golding J, Lemeshow S, Phillips G, Lamb K, Stoltenberg C, Håberg SE, Strőm M, Granstrőm C, Northstone K, Klebanoff M, Ponsonby A-L, Milne E et al. Birthweight and childhood cancer: preliminary findings from the International Childhood Cancer Cohort Consortium (I4C). Paediatric and Perinatal Epidemiology 2015:29(4); 335-345.
- Greenop KR, Bailey HD, Miller M, Scott RJ, Attia J, Ashton LJ, Downie P, Armstrong BK, Milne E. Breastfeeding and nutrition to 2 years of age and risk of childhood acute lymphoblastic leukemia and brain tumors. Nutrition & Cancer. 2015:67:3, 431-441, DOI: 10.1080/01635581.2015.998839
- Rudant, J, Lightfoot T, Urayama K, Petridou E, Dockerty JD, Magnani C, Milne E, et al. Childhood acute lymphoblastic leukemia and indicators of early immune stimulation: a Childhood Leukemia International Consortium Study. American Journal of Epidemiology 2015. 181(8):549-62. doi: 10.1093/aje/kwu298. Epub 2015 Mar 1.
- Dawson S, Charles AK, Bower C, de Klerk NH, Milne E. Risk of cancer among children with birth defects: a novel approach. Birth Defects Research Part A. 2015;103:283–290. Doi: 10.1002/bdra.23364
- Milne E, Greenop KR, Scott RJ, Haber M, Norris MD, Attia J, Jamieson SE, Miller M, Bower C, Bailey HD, Dawson S, McGowage GB, de Klerk NH, van Bockxmeer FM, Armstrong BK Folate pathway gene polymorphisms, maternal folic acid use and risk of childhood acute lymphoblastic leukemia. Cancer Epidemiology, Biomarkers and Prevention 2015;24(1): 48-56