Toll-like receptor 2 ligands inhibit Th2 responses to mite allergen

There is intense interest in the interaction between microbial compounds and allergy.

Authors:
Taylor R, Richmond P, Upham J

Authors notes:
J Allergy Clinical Immunology 2006;117:1148-54

Keywords:
Toll-like receptor 2 ligands inhibit Th2 responses to mite allergen

Abstract:
There is intense interest in the interaction between microbial compounds and allergy. Although Toll-like receptor (TLR)-2 ligands derived from Gram-positive bacteria alter allergic sensitization in animal models, it is not clear what effect TLR2 ligands have on allergen-specific T-cell memory in human beings.