Authors:
Gorman S, McGlade JP, Lambert MJ, Strickland DH, Thomas JA, Hart PH
Authors notes:
Photochemical and Photobiological Sciences 2010;9:571-77
Keywords:
UV exposure, allergic airways disease
Abstract:
Asthma is a chronic inflammatory disease of the small and large conducting airway mucosa characterised by Th2 cell immunity. Allergen-specific IgE levels control the immediate response whilst the interplay between airway mucosal antigen presenting cells, Th2 effector cells and CD4+CD25+ regulatory T cells control the late phase, cell-mediated response.