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MEIS proteins as partners of the TLX1/HOX11 oncoprotein

Aberrant expression of the TLX1/HOX11 proto-oncogene is associated with a significant subset of T-cell acute lymphoblastic leukemias...

Authors:
Milech N, Gottardo NG, Ford J, D'Souza D, Greene WK, Kees UR, Watt PM.

Authors notes:
Leuk Res. 2010 Mar;34(3):358-63. Epub 2009 Jun 25.

Keywords:
MEIS proteins, partners, TLX1/HOX11 oncoprotein

Abstract:
Aberrant expression of the TLX1/HOX11 proto-oncogene is associated with a significant subset of T-cell acute lymphoblastic leukemias (T-ALL). Yet the manner in which TLX1 contributes to oncogenesis is not fully understood