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Exposure to diagnostic radiological procedures and the risk of childhood acute lymphoblastic leukemia

Diagnostic irradiation of the mother during pregnancy increases the risk of childhood acute lymphoblastic leukemia

Authors:
Bailey HD, Armstrong BK, de Klerk NH, Fritschi L, Attia J, Lockwood L, Milne E.

Authors notes:
Cancer Epidemiology, Biomarkers and Prevention 2010;19:2897-909.

Keywords:
Exposure, diagnostic radiological procedures, risk of childhood acute lymphoblastic leukemia, ALL, diagnostic irradiation, mother during pregnancy, childhood diagnostic irradiation, diagnostic x-rays

Abstract:
Diagnostic irradiation of the mother during pregnancy increases the risk of childhood acute lymphoblastic leukemia (ALL). There is inconsistent evidence on associations between ALL and other parental or childhood diagnostic irradiation. The aim of this analysis is to investigate whether diagnostic X-rays of the mother before birth, of the father before conception, or of the child increased the risk of childhood ALL.