Identifying peroxidases and their oxidants in the early pathology of cystic fibrosis

We aimed to determine whether myeloperoxidase (MPO) is the main peroxidase present in the airways of children with cystic fibrosis (CF) and to assess which oxid

Authors:

Thomson E, Brennan S, Senthilmohan R, Gangell CL, Chapman AL, Sly PD, Kettle AJ

Authors notes:

Free Radic Biol Med. 2010 Nov 15;49(9):1354-60. Epub 2010 Jul 18.

Keywords:

identifying, peroxidases, oxidants, early pathology, cystic fibrosis, myeloperoxidase, MPO, airways of children, assess, clinical features, CF

Abstract:

We aimed to determine whether myeloperoxidase (MPO) is the main peroxidase present in the airways of children with cystic fibrosis (CF) and to assess which oxidants it produces and whether they are associated with clinical features of CF.