CD4 allergen tetramers

The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties...

Authors:
Thomas, W. R.

Authors notes:
Clinical and Experimental Allergy. 2011;41(6):769-72

Keywords:
CD4 allergen tetramers, antigen-binding CD41 cells, recombinant MHC scaffolds, allergen, peptide-binding

Abstract:
The introduction of class II tetramers for identifying antigen-binding CD41 cells has lagged behind the use of class I tetramers because of difficulties in producing the recombinant MHC scaffolds.