Hospitalisation with infection, asthma and allergy in Kawasaki disease patients and their families: genealogical analysis using linked population data

Kawasaki disease results from an abnormal immunological response to one or more infectious triggers.

Authors:
Webster RJ, Carter KW, Warrington NM, Loh AM, Zaloumis S, Kuijpers TW, Palmer LJ and Burgner DP

Authors notes:
PLoS One 6(11):e28004. Epub 2011 Nov 28.

Keywords:
Hospitalisation with infection, asthma, allergy, Kawasaki disease patients, families, genealogical analysis, linked population data

Abstract
Kawasaki disease results from an abnormal immunological response to one or more infectious triggers. We hypothesised that heritable differences in immune responses in Kawasaki disease-affected children and their families would result in different epidemiological patterns of other immune-related conditions. We investigated whether hospitalisation for infection and asthma/allergy were different in Kawasaki disease-affected children and their relatives.