Authors:
Johnson, S. R.; Nolan, R. C.; Grant, M. T.; Price, G. J.; Siafarikas, A.; Bint, L.; Choong, C. S. Y.
Authors notes:
Journal of Paediatrics and Child Health. 2012;48(3):E136-E9
Keywords:
precocious puberty, sterile abscess, follitropin, gonadorelin, leuprorelin, luteinizing hormone, abscess, antibiotic therapy
Abstract
We describe a case of an 8 year old girl with central precocious puberty. She was commenced on 3 monthly intramuscular depot Leuprorelin acetate therapy, as a result of which she developed sterile abscesses. She was converted to daily subcutaneous Leuprorelin acetate therapy with no recurrence of the abscesses. The possible mechanisms for this reaction are described in the article.