Authors:
Mott LS, Graniel KG, Park J, De Klerk NH, Sly PD, Murray CP, Tiddens HAWM, Stick SM
Authors notes:
Chest. 2013;144(4):1193-1198
Keywords:
Cystic fibrosis, CT-scan, bronchiectasis, lung volume
Abstract:
The aim of this study was to determine whether assessment of early CT scan-detected bronchiectasis in young children with cystic fibrosis (CF) depends on lung volume.
Expiratory scans had poor sensitivity to detect bronchiectasis, underestimating disease extent.
Airway:vessel ratios were consistently higher in inspiration, independent of age and vessel size, with significantly more airways visible in inspiration than in expiration, independent of age.
In young children with CF, radiologic assessment of early bronchiectasis with chest CT scan depends on lung volume; thus, expiratory scans may not be appropriate for evaluating bronchiectasis in this population.
Lung volume during CT image acquisition should be standardized to evaluate airway dimensions in young children.