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Physical inactivity is associated with moderate-severe obstructive sleep apnea

To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA).

Authors:
Simpson L, McArdle N, Eastwood PR, Ward KL, Cooper MN, Wilson AC, et al.

Authors notes:
J Clin Sleep Med. 2015;11(10):1091-9A

Keywords:
Cardio metabolic, Exercise, Occupation, Sleep disordered breathing, Weight

Abstract:
Study Objectives: To investigate whether low levels of physical activity were associated with an increased occurrence of obstructive sleep apnea (OSA), OSA-related symptoms, and cardiometabolic risk.

Methods: A case-control study design was used.

OSA cases were patients referred to a sleep clinic for suspected OSA (n = 2,340).

Controls comprised participants from the Busselton community (n = 1,931).

Exercise and occupational activity were derived from questionnaire data.

Associations were modelled using logistic and linear regression and adjusted for confounders.

Results: In comparison with moderate exercise, the high, low, and nil exercise groups had an odds ratio (OR) for moderate-severe OSA of 0.6, 1.6, and 2.7, respectively.

Relative to men in heavy activity occupations, men in medium, light and sedentary occupations had an OR for moderate-severe OSA of 1.7, 2.1, and 1.8, respectively.

Relative to women in medium activity occupations, women in light and sedentary occupations had an OR for moderate-severe OSA of 4.2 and 3.5.

OSA patients who adequately exercised had lower: levels of doctor-diagnosed depression; symptoms of fatigue; systolic and diastolic blood pressure; and C-reactive protein (CRP).

Conclusions: Low levels of physical activity were associated with moderate-severe OSA.

Exercise in individuals with OSA is associated with lower levels of depression, fatigue, blood pressure and CRP.