Citation:
Stenström B, Windsor HM, Fulurija A, Benghezal M, Kumarasinghe MP, Kimura K, et al. Helicobacter pylori overcomes natural immunity in repeated infections. Clinical Case Reports. 2016;4(11):1026-33
Keywords:
Helicobacter; natural immunity; reinfection; vaccination
Abstract:
Repeated experimental reinfection of two subjects indicates that Helicobacter pylori infection does not promote an immune response protective against future reinfection. Our results highlight the importance of preventing reinfection after eradication, through public health initiatives, and possibly treatment of family members. They indicate difficulties for vaccine development, especially therapeutic vaccines.