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CrossTalk opposing view: Mucosal acidification does not drive early progressive lung disease in cystic fibrosis

Whether airway mucosal acidification drives early progressive lung disease is controversial

Citation:
Stick SM, Schultz A. CrossTalk opposing view: Mucosal acidification does not drive early progressive lung disease in cystic fibrosis. Journal of Physiology. 2018;596(16):3439-41

Abstract:
Whether airway mucosal acidification drives early progressive lung disease is controversial. Our argument that other factors are more important in the early pathogenesis of cystic fibrosis lung disease is supported by unique data obtained from very young children with cystic fibrosis and age-matched controls.