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Estimation of the force of infection and infectious period of skin sores in remote Australian communities using interval-censored data

Prevalence of impetigo (skin sores) remains high in remote Australian Aboriginal communities, Fiji, and other areas of socio-economic disadvantage. Skin sore infections, driven primarily in these settings by Group A Streptococcus (GAS) contribute substantially to the disease burden in these areas. Despite this, estimates for the force of infection, infectious period and basic reproductive ratio-all necessary for the construction of dynamic transmission models-have not been obtained.

Citation:
Lydeamore MJ, Campbell PT, Price DJ, Wu Y, Marcato AJ, ....  Carapetis JR et al. Estimation of the force of infection and infectious period of skin sores in remote Australian communities using interval-censored data. PLoS Comput Biol. 2020;16(10):e1007838.

Keywords:
Impetigo; skin sores; Australian Aboriginal communities; Fiji; Group A Streptococcus; infection

Abstract:
Prevalence of impetigo (skin sores) remains high in remote Australian Aboriginal communities, Fiji, and other areas of socio-economic disadvantage. Skin sore infections, driven primarily in these settings by Group A Streptococcus (GAS) contribute substantially to the disease burden in these areas. Despite this, estimates for the force of infection, infectious period and basic reproductive ratio-all necessary for the construction of dynamic transmission models-have not been obtained.