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Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q

Within PF-EPN-A, 1q gain is a marker of poor prognosis, however, it is unclear if within PF-EPN-A additional cytogenetic events exist which can refine risk stratification.

Citation:
Baroni LV, Sundaresan L, Heled A, Coltin H, ……..Gottardo N, Kool M, et al. Ultra high-risk PFA ependymoma is characterized by loss of chromosome 6q. Neuro Oncol. 2021;23(8):1360-70.

Keywords:
Chromosome Aberrations; Chromosomes; Ependymoma/genetics; Microarray Analysis; Progression-Free Survival; ependymoma;
subgrouping

Abstract:
Within PF-EPN-A, 1q gain is a marker of poor prognosis, however, it is unclear if within PF-EPN-A additional cytogenetic events exist which can refine risk stratification.