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Case Report: Neonatal Varicella Acquired From Maternal Zoster

The incidence of neonatal varicella has decreased dramatically since the introduction of the varicella vaccination. Although the varicella zoster virus is often associated with a mild infection, it may cause severe morbidity and mortality, particularly in the neonatal period and immunocompromised hosts. We report a case of neonatal varicella acquired from maternal zoster in a mother on biological immunosuppressive therapy.

Citation:
Lai JW, Ford T, Cherian S, Campbell AJ, Blyth CC. Case Report: Neonatal Varicella Acquired From Maternal Zoster. Front Pediatr. 2021;9.

Keywords:
Maternal immunosuppression; maternal zoster; neonatal varicella; trans-placental immunity; varicella zoster immune globulin

Abstract:
The incidence of neonatal varicella has decreased dramatically since the introduction of the varicella vaccination. Although the varicella zoster virus is often associated with a mild infection, it may cause severe morbidity and mortality, particularly in the neonatal period and immunocompromised hosts. We report a case of neonatal varicella acquired from maternal zoster in a mother on biological immunosuppressive therapy.