Influences on the trajectory and subsequent outcomes in CDKL5 deficiency disorder

Citation:
Leonard H, Junaid M, Wong K, Aimetti AA, Pestana Knight E, Downs J. Influences on the trajectory and subsequent outcomes in CDKL5 deficiency disorder. Epilepsia. 2021.

Keywords:
CDKL5 deficiency disorder; developmental and epileptic encephalopathy; developmental trajectory; quality of life; seizure burden

Abstract:
The study investigated the effect of seizure and medication burden at initial contact with the International CDKL5 Disorder Database on subsequent development and clinical severity and compared quality of life among those whose development progressed, remained stable, or regressed between baseline and follow-up.