Antimalarials for children with Plasmodium vivax infection: Current status, challenges, and research priorities

The aim of this narrative review is to summarise efficacy and pharmacokinetic data for Plasmodium vivax in children. The burden of P. vivax malaria in children continues to remain a significant public health issue, and the need for improved treatment regimens for this vulnerable population is critical.

Citation:
Woon SA, Manning L, Moore BR. Antimalarials for children with Plasmodium vivax infection: Current status, challenges, and research priorities. Parasitol Int. 2022;87.

Keywords:
Artemisinin combination therapy; Paediatrics; Pharmacokinetics; Pharmacotherapy; Plasmodium vivax; Primaquine, chloroquine, tafenoquine

Abstract:
The aim of this narrative review is to summarise efficacy and pharmacokinetic data for Plasmodium vivax in children. The burden of P. vivax malaria in children continues to remain a significant public health issue, and the need for improved treatment regimens for this vulnerable population is critical.