Parental preconception BMI trajectories from childhood to adolescence and asthma in the future offspring

Recent evidence suggests that parental exposures before conception can increase the risk of asthma in offspring. We investigated the association between parents' preconception body mass index (BMI) trajectories from childhood to adolescence and subsequent risk of asthma in their offspring.

Citation:
Bowatte G, Bui DS, Priyankara S, Lowe AJ, Perret JL, Martino D… et al. Parental preconception BMI trajectories from childhood to adolescence and asthma in the future offspring. J Allergy Clin Immunol. 2022.

Keywords:
Asthma; Body mass index; epigenetics; intergenerational; preconception; transgenerational

Abstract:
Recent evidence suggests that parental exposures before conception can increase the risk of asthma in offspring. We investigated the association between parents' preconception body mass index (BMI) trajectories from childhood to adolescence and subsequent risk of asthma in their offspring.