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Protocol of DREAM3R: DuRvalumab with chEmotherapy as first-line treAtment in advanced pleural Mesothelioma-a phase 3 randomised trial

There is a strong theoretical rationale for combining checkpoint blockade with cytotoxic chemotherapy in pleural mesothelioma and other cancers.

Citation:
Kok PS, Forde PM, Hughes B, Sun Z, Brown C, ……. Lesterhuis WJ, Yip S, O’Byrne K, et al. Protocol of DREAM3R: DuRvalumab with chEmotherapy as first-line treAtment in advanced pleural Mesothelioma-a phase 3 randomised trial. BMJ Open. 2022;12(1):e057663.

Keywords:
Chemotherapy; immunology; oncology; respiratory tract tumours

Abstract:
There is a strong theoretical rationale for combining checkpoint blockade with cytotoxic chemotherapy in pleural mesothelioma and other cancers.