Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort study

There is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments.

Citation:
Sanna F, Locatelli F, Sly PD, White E, ……… Hall GL, Foong RE. Characterisation of lung function trajectories and associated early-life predictors in an Australian birth cohort study. ERJ Open Res. 2022;8(1).

Keywords:
Nitrogen dioxide; air pollution; asthma; atopy; birth cohort; birth weight; child health; cohort analysis; eczema; environmental exposure; environmental factor; food allergy; forced expiratory volume; forced vital capacity; lung function; major clinical study; maternal smoking; pollen allergy; pregnancy; prospective study; respiratory tract disease; spirometry; wheezing

Abstract:
There is growing evidence that lung function in early-life predicts later lung function. Adverse events over the lifespan might influence an individual’s lung function trajectory, resulting in poor respiratory health. The aim of this study is to identify early-life risk factors and their impact on lung function trajectories to prevent long-term lung impairments.