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Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers

The bacille Calmette-Guérin (BCG) vaccine has immunomodulatory "off-target" effects that have been hypothesized to protect against coronavirus disease 2019. 

Citation:
Pittet LF, Messina NL, Orsini F, ....... Kollmann TR, Lacerda MVG, ....... Manning L, Marshall HS, ........ Richmond PC, Rodriguez-Bano J, et al. Randomized Trial of BCG Vaccine to Protect against Covid-19 in Health Care Workers. N Engl J Med. 2023;388(17):1582-96.

Keywords:
Adjuvants; immunology; BCG Covid-19; vaccines; therapeutic use; prevention & control; double-blind method; Sars-Cov-2

Abstract:
The bacille Calmette-Guérin (BCG) vaccine has immunomodulatory "off-target" effects that have been hypothesized to protect against coronavirus disease 2019.