Identification of subgroups of children in the Australian Autism Biobank using latent class analysis

The identification of reproducible subtypes within autistic populations is a priority research area in the context of neurodevelopment, to pave the way for identification of biomarkers and targeted treatment recommendations. Few previous studies have considered medical comorbidity alongside behavioural, cognitive, and psychiatric data in subgrouping analyses.

Citation:
Montgomery A, Masi A, Whitehouse A, Veenstra-VanderWeele J, ....... Alvares G, Woolfenden S, et al. Identification of subgroups of children in the Australian Autism Biobank using latent class analysis. Child Adolesc Psychiatry Ment Health. 2023;17(1):27.

Keywords:
Autism spectrum; Latent class analysis; Subgroups.

Abstract:
The identification of reproducible subtypes within autistic populations is a priority research area in the context of neurodevelopment, to pave the way for identification of biomarkers and targeted treatment recommendations. Few previous studies have considered medical comorbidity alongside behavioural, cognitive, and psychiatric data in subgrouping analyses.