Gut Microbiome and Associated Metabolites Following Bariatric Surgery and Comparison to Healthy Controls

The gut microbiome plays a significant role in regulating the host’s ability to store fat, which impacts the development of obesity. This observational cohort study recruited obese adult men and women scheduled to undergo sleeve gastrectomy and followed up with them 6 months post-surgery to analyse their microbial taxonomic profiles and associated metabolites in comparison to a healthy control group.

Citation:
Ahmad AF, Caparrós-Martín JA, Lee S, O’Gara F, Yeap BB, Green DJ, Ballal M, Ward NC, Dwivedi G. Gut Microbiome and Associated Metabolites Following Bariatric Surgery and Comparison to Healthy Controls. Microorg. 2023;11(5)

Keywords:
Bariatric surgery; cardiovascular disease; dysbiosis; gut microbiome; obesity; short chain fatty acids

Abstract:
The gut microbiome plays a significant role in regulating the host’s ability to store fat, which impacts the development of obesity. This observational cohort study recruited obese adult men and women scheduled to undergo sleeve gastrectomy and followed up with them 6 months post-surgery to analyse their microbial taxonomic profiles and associated metabolites in comparison to a healthy control group.