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Left ventricular remodelling in rheumatic heart disease – trends over time and implications for follow-up in childhood

Rheumatic heart disease (RHD) is the most common form of acquired heart disease worldwide. In RHD, volume loading from mitral regurgitation leads to left ventricular (LV) dilatation, increased wall stress, and ultimately LV dysfunction. Improved understanding of LV dynamics may contribute to refined timing of intervention.

Citation:
MacDonald B, Tarca A, Causer L, Maslin K, Bruce D, Schreiber-Wood R, Kumar M, Ramsay J, Andrews D, Budgeon C, Katzenellenbogen J, Bowen AC, Carapetis J, Friedberg MK, Yim D. Left ventricular remodelling in rheumatic heart disease – trends over time and implications for follow-up in childhood. BMC Cardiovasc Disord. 2023;23(1).

Keywords:
Left ventricle volume; Left ventricular remodelling; Rheumatic heart disease (RHD)

Abstract:
Rheumatic heart disease (RHD) is the most common form of acquired heart disease worldwide. In RHD, volume loading from mitral regurgitation leads to left ventricular (LV) dilatation, increased wall stress, and ultimately LV dysfunction. Improved understanding of LV dynamics may contribute to refined timing of intervention.