Applying causal inference and Bayesian statistics to understanding vaccine safety signals using a simulation study

Community perception of vaccine safety influences vaccine uptake. Our objective was to assess current vaccine safety monitoring by examining factors that may influence the availability of post-vaccination survey data, and thereby the specificity and sensitivity of existing signal detection methods.

Citation:
Tay E, Dymock M, Lopez L, ……. Snelling T, Marsh JA, Wu Y. Applying causal inference and Bayesian statistics to understanding vaccine safety signals using a simulation study. npj Vaccines. 2024;9(1).

Keywords:
SARS-CoV-2 vaccine; Bayes theorem; disease severity; drug safety; monitoring

Abstract:
Community perception of vaccine safety influences vaccine uptake. Our objective was to assess current vaccine safety monitoring by examining factors that may influence the availability of post-vaccination survey data, and thereby the specificity and sensitivity of existing signal detection methods.