Invasive Fungal Disease in Immunocompromised Children: Current and Emerging Therapies

In an era of expanding indications for iatrogenic immunosuppression, invasive fungal disease (IFD) remains a significant challenge in immunocompromised children, with case fatality rates ranging from 10 to 70%. Understanding of current recommendations and recent evidence is essential to guide optimal IFD management.

Citation:
Brophy-Williams S, Ewe KYH, Yeoh DK. Invasive Fungal Disease in Immunocompromised Children: Current and Emerging Therapies. Curr Infect Dis Rep. 2024;26(12):235-44.

Keywords:
Antifungals; Children; Immunotherapy; Invasive fungal disease

Abstract:
In an era of expanding indications for iatrogenic immunosuppression, invasive fungal disease (IFD) remains a significant challenge in immunocompromised children, with case fatality rates ranging from 10 to 70%. Understanding of current recommendations and recent evidence is essential to guide optimal IFD management.