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Prenatal Origins of Obstructive Airway Disease: Starting on the Wrong Trajectory?

From the results of well-performed population health studies, we now have excellent data demonstrating that deficits in adult lung function may be present early in life, possibly as a result of developmental disorders, incurring a lifelong risk of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease. 

Citation:
Wang KCW, James AL, Donovan GM, Noble PB. Prenatal Origins of Obstructive Airway Disease: Starting on the Wrong Trajectory? Compr Physiol. 2024;14(5):5729-62.

Keywords:
Fetal development; physiology; lung disease; etiology; physiopathology; pregnancy; prenatal exposure

Abstract:
From the results of well-performed population health studies, we now have excellent data demonstrating that deficits in adult lung function may be present early in life, possibly as a result of developmental disorders, incurring a lifelong risk of obstructive airway diseases such as asthma and chronic obstructive pulmonary disease.