State transitions across the Strep A disease spectrum: scoping review and evidence gaps

The spectrum of diseases caused by Streptococcus pyogenes (Strep A) ranges from superficial to serious life-threatening invasive infections. We conducted a scoping review of published articles between 1980 and 2021 to synthesize evidence of state transitions across the Strep A disease spectrum. We identified 175 articles reporting 262 distinct observations of Strep A disease state transitions.

Citation:
Parajulee P, Lee JS, Abbas K, Cannon J, Excler JL, et al. State transitions across the Strep A disease spectrum: scoping review and evidence gaps. BMC Infect Dis. 2024;24(1):108

Keywords:
Acute poststreptococcal glomerulonephritis; Acute rheumatic fever; Group A Streptococcus; Invasive disease; Pharyngitis; Rheumatic heart disease; Scoping review; Skin infection; State transition

Abstract:
The spectrum of diseases caused by Streptococcus pyogenes (Strep A) ranges from superficial to serious life-threatening invasive infections. We conducted a scoping review of published articles between 1980 and 2021 to synthesize evidence of state transitions across the Strep A disease spectrum. We identified 175 articles reporting 262 distinct observations of Strep A disease state transitions.