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Brain iron concentration in childhood ADHD: A systematic review of neuroimaging studies

Iron deficiency may play a role in the pathophysiology of Attention Deficit/Hyperactivity Disorder (ADHD). Due to its preponderant function in monoamine catecholamine and myelin synthesis, brain iron concentration may be of primary interest in the investigation of iron dysregulation in ADHD.

Citation:
Morandini HAE, Watson PA, Barbaro P, Rao P. Brain iron concentration in childhood ADHD: A systematic review of neuroimaging studies. J Psychiatr Res. 2024;173:200-9.

Keywords:
ADHD; Adolescents; Brain iron; Children; Magnetic resonance imaging; Neuroimaging

Abstract:
Iron deficiency may play a role in the pathophysiology of Attention Deficit/Hyperactivity Disorder (ADHD). Due to its preponderant function in monoamine catecholamine and myelin synthesis, brain iron concentration may be of primary interest in the investigation of iron dysregulation in ADHD.