Malaria treatment for prevention: a modelling study of the impact of routine case management on malaria prevalence and burden

Testing and treating symptomatic malaria cases is crucial for case management, but it may also prevent future illness by reducing mean infection duration. Measuring the impact of effective treatment on burden and transmission via field studies or routine surveillance systems is difficult and potentially unethical. This project uses mathematical modeling to explore how increasing treatment of symptomatic cases impacts malaria prevalence and incidence.

Citation:
Camponovo F, Jeandron A, Skrip LA, ……. Symons TL, Connell M, Gething PW, Visser T, et al. Malaria treatment for prevention: a modelling study of the impact of routine case management on malaria prevalence and burden. BMC Infect Dis. 2024;24(1):1267.

Keywords:
Malaria; Modelling; P. Falciparum; Transmission; Treatment

Abstract:
Testing and treating symptomatic malaria cases is crucial for case management, but it may also prevent future illness by reducing mean infection duration. Measuring the impact of effective treatment on burden and transmission via field studies or routine surveillance systems is difficult and potentially unethical. This project uses mathematical modeling to explore how increasing treatment of symptomatic cases impacts malaria prevalence and incidence.