Phage therapy to treat cystic fibrosis Burkholderia cepacia complex lung infections: perspectives and challengesge

Burkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.

Citation:
Canning JS, Laucirica DR, Ling KM, Nicol MP, Stick SM, Kicic A. Phage therapy to treat cystic fibrosis Burkholderia cepacia complex lung infections: perspectives and challenges. Front Microbiol. 2024;15

Keywords:
Burkholderia; antimicrobial resistance; bacteriophage; cystic fibrosis; phage therapy

Abstract:
Burkholderia cepacia complex is a cause of serious lung infections in people with cystic fibrosis, exhibiting extremely high levels of antimicrobial resistance. These infections are difficult to treat and are associated with high morbidity and mortality.