Pregnancy with multiple high-risk factors: a systematic review and meta-analysis

A wide spectrum of high-risk factors in pregnancy can lead to adverse pregnancy outcomes or short- or long-term health effects. Despite this, there has been no synthesis of findings on the measurement, potential causes, and health outcomes of multiple high-risk factors in pregnancy. We aimed to address this gap by summarising the existing research on this topic.

Citation:
Zhang Y, Ding W, Wu T, …….. Adane AA, Dai X, et al. Pregnancy with multiple high-risk factors: a systematic review and meta-analysis. J Glob Health. 2025;15:04027.

Keywords:
Pregnancy; complications; epidemiology; outcomes; risk factors

Abstract:
A wide spectrum of high-risk factors in pregnancy can lead to adverse pregnancy outcomes or short- or long-term health effects. Despite this, there has been no synthesis of findings on the measurement, potential causes, and health outcomes of multiple high-risk factors in pregnancy. We aimed to address this gap by summarising the existing research on this topic.