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Chewing gum to treat postoperative nausea and vomiting in female patients: a multicenter randomized trial

Postoperative nausea and vomiting is common after general anesthesia, with consequences for patient outcomes, satisfaction with care, and healthcare costs. The aim was to compare a new treatment, chewing gum, with a widely used intravenous agent, ondansetron, to treat postoperative nausea and vomiting in female patients in the postanesthesia care unit.

Citation:
Darvall JN, De Silva AP, von Ungern-Sternberg B, Story DA, et al.  Chewing gum to treat postoperative nausea and vomiting in female patients: a multicenter randomized trial. Anesthesiology. 2025;142(3):454-464.

Keywords:
antiemetics; administration; dosage; therapeutic use; chewing gum; Ondansetron; postoperative neasuea and vomiting; prevention; control

Abstract:
Postoperative nausea and vomiting is common after general anesthesia, with consequences for patient outcomes, satisfaction with care, and healthcare costs. The aim was to compare a new treatment, chewing gum, with a widely used intravenous agent, ondansetron, to treat postoperative nausea and vomiting in female patients in the postanesthesia care unit.