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Reports and Findings

Research

Developing new models of mitochondrial diseases using CRISPR/Cas technologies

Aleksandra Filipovska BSc PhD Louis Landau Chair in Child Health Research; NHMRC Leadership Fellow; Deputy Director, ARC Centre of Excellence for Synthetic Biology; Adjunct Research Professor, Monash University Louis Landau Chair in Child Health

Research

A pilot study into assessing the danger of heated-tobacco-products

Alexander Anthony Dr Katherine Larcombe Kicic Landwehr BScEnv (Hons) PhD BSc (Hons) PhD BSc(Hons) Head, Respiratory Environmental Health Rothwell Family Fellow; Head, Airway Epithelial Research Senior Research Officer Anthony.Kicic@thekids.org.au

Research

Chemical analysis of new and “aged” e-liquids: Development of a rapid toxicological screening approach

Alexander Larcombe BScEnv (Hons) PhD Head, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at The Kids in 2005 and is now a Senior Research Fellow and Head of the

Research

Lung function in a model of a paediatric metabolic disease

Alexander Larcombe BScEnv (Hons) PhD Head, Respiratory Environmental Health Team Leader, Respiratory Environmental Health Associate Professor Alexander Larcombe began work at The Kids in 2005 and is now a Senior Research Fellow and Head of the

Research

Innate Immune Training for Prevention of Recurrent Wheeze in Early Childhood

Pat Deborah Holt Strickland PhD, DSc, FRCPath, FRCPI, FAA PhD Emeritus Honorary Researcher Program Head, Immunobiology and Immunotherapeutic Program Patrick.Holt@thekids.org.au Deb.Strickland@thekids.org.au Emeritus Honorary Researcher Program Head

Research

Viridans Group Streptococci in Pediatric Leukemia and Stem Cell Transplant: Review of a Risk-stratified Guideline for Empiric Vancomycin in Febrile Neutropenia

Viridans group streptococci (VGS) are an important cause of sepsis in immunosuppressed children. We reviewed the effectiveness of risk-stratified addition of vancomycin to empiric febrile neutropenia therapy among 107 children with leukemia or undergoing an allogeneic transplant.

Research

SYNERGY CF: Getting the best start to life - preventing early cystic fibrosis lung disease by solving the host-inflammation infection conundrum

Anthony Stephen Yuliya Kicic Stick Karpievitch BSc (Hons) PhD MB BChir PhD MRCP FRACP PhD, MS, BS Rothwell Family Fellow; Head, Airway Epithelial Research Head, P4 Respiratory Health for Kids AI and Data Analytics Lead, Respiratory Research +

Research

Description of Total Population Hospital Admissions for Treacher Collins Syndrome in Australia

To describe patterns and demographic characteristics of total-population hospital admissions with a diagnosis of Treacher Collins syndrome (TCS) in Australia.

Research

Use of parenteral nutrition in term and late preterm infants: An Australian and New Zealand Survey

There is limited information regarding the use of parenteral nutrition (PN) in term and late preterm infants. We conducted a survey to study the current clinical practices within Australia and New Zealand (ANZ). A 15-question online-survey was distributed to 232 neonatologists and 55 paediatric intensivists across ANZ between September and November 2019.

Research

Prenatal Exposure to General Anesthesia and Childhood Behavioral Deficit

Exposure to surgery and anesthesia in early childhood has been found to be associated with an increased risk of behavioral deficits. While the US Food and Drug Administration (FDA) has warned against prenatal exposure to anesthetic drugs, little clinical evidence exists to support this recommendation.