Reports and Findings
Research
Changes in risk factors for preterm birth in Western Australia 1984-2006Marked increases in maternal age and primiparous births were observed. A four-fold increase in the rates of pre-existing medical complications over time...
Research
Hypomethylation of the CTGF gene locus is a common feature of paediatric pre-B acute lymphoblastic leukaemiaWe identified consistent hypomethylation of the CTGF locus in primary pre-B ALL specimens regardless of CTGF expression.
Research
A time series analysis of presentations to Queensland health facilities for alcohol-related conditions, following the increase in 'alcopops' taxWe measured changes in admissions for alcohol-related harm to health throughout Queensland, before and after the tax increase in April 2008.
Research
Analysis of baseline hypothalamic-pituitary-adrenal activity in late adolescence reveals gender specific sensitivity of the stress axisWe aimed to investigate basal HPA-activity in a normal population in late adolescence, the time of life believed to overlap with HPA-axis maturation...
Research
A novel retro-inverso peptide is a preferential JNK substrate-competitive inhibitorA novel 18 amino acid peptide PYC98 was demonstrated to inhibit JNK1 activity toward c-Jun.
Research
Utility of auscultatory screening for detecting rheumatic heart disease in high-risk children in Australia's Northern TerritorySensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator.
Research
Species-Specific and Cross-Reactive IgG1 Antibody Binding to Viral Capsid Protein 1 (VP1) Antigens of Human Rhinovirus Species A, B and CHuman rhinoviruses (HRV) are associated with upper and lower respiratory illnesses, including severe infections causing hospitalization in both children...
Research
Admissions in Children with Down Syndrome: Experience of a Population-Based Cohort Followed from BirthThis study describes patterns of hospitalisations for children and young people with Down syndrome in Western Australia.
Research
A Genome-Wide Search for Type 2 Diabetes Susceptibility Genes in an Extended Arab FamilyWe performed a discovery GWAS in an extended UAE family (N = 178; 66 diabetic; 112 healthy) genotyped on the Illumina Human 660 Quad Beadchip, with...
Research
Effects of adopting the new global lung function initiative 2012 reference equations on the interpretation of spirometryThe aim of this study was to document the likely interpretative effects of changing from commonly used current spirometry reference equations to the GLI2012...