Investigators: Desiree Silva, Elayne Downie, Jason Tan, Peter Richmond, Ravisha Srinivas Jois, Sanjay Patole
This is a prospective double blinded, randomized case-control trial conducted within the neonatal intensive care unit (NICU) at Joondalup Health Campus to determine whether probiotics will correct antibiotic-induced dysbiosis in term newborns after early life antibiotic exposure.
We will explore the effect of antibiotics in newborn infants, determine whether probiotics may have a positive effect on the intestinal microbiome of these newborn infants and whether this effect may translate to improved gastrointestinal health in the form of reduced gastro-oesophageal reflux and infant colic.