Investigators: Nat Eiffler, Rym Ben Othman, Stephen Stick, Tobi Kollmann
Project description
Chile has been hard hit by COVID-19, at times reporting around 6500 new cases a day, with many of these located in the capital Santiago. Researchers from the Systems Vaccinology team have worked with local and international collaborators to run the Containing Coronavirus Disease 19 clinical trial (ConCorD-19) in Santiago.
ConCorD-19 is recruiting more than 300 Santiago households where there is a positive COVID-19 case and delivering interferon therapy or standard care to all household members. Each household will be closely tracked over a month to see whether interferon beta treatment can reduce the spread, severity and duration of COVID-19. Previous clinical trials have shown that interferon therapy was safe and offered protection against other coronaviruses (including SARS and MERS), making it a promising treatment option for regions hard hit by COVID-19 during the wait for effective COVID-19 vaccines.
Chile has been hard hit by COVID-19, at times reporting around 6500 new cases a day, with many of these located in the capital Santiago. Researchers from the Systems Vaccinology team have worked with local and international collaborators to run the Containing Coronavirus Disease 19 clinical trial (ConCorD-19) in Santiago.
ConCorD-19 is recruiting more than 300 Santiago households where there is a positive COVID-19 case and delivering interferon therapy or standard care to all household members. Each household will be closely tracked over a month to see whether interferon beta treatment can reduce the spread, severity and duration of COVID-19. Previous clinical trials have shown that interferon therapy was safe and offered protection against other coronaviruses (including SARS and MERS), making it a promising treatment option for regions hard hit by COVID-19 during the wait for effective COVID-19 vaccines.
External collaborators
- Eleanor Fish (University Health Network, Toronto General Hospital Research Institute)
- Arturo Borzutzky (University of Pontificia Universidad Católica de Chile)
- Jose A. Castro-Rodriguez (University of Pontificia Universidad Católica de Chile)