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Discover . Prevent . Cure .

Development of new preclinical models of childhood leukaemia

Investigators: Sebastien Malinge, Laurence Cheung, Rishi Kotecha

Project description

Leukaemia accounts for a third of cancers diagnosed in children worldwide. Modern treatment protocols have risk-stratified patients according to genetic features of their leukaemia cells, which has significantly improved the outcome for children with leukaemia. The precise characterisation of the genetic mutations found in human leukaemia are associated with a better understanding of how leukaemia is initiated and progresses, and will ultimately open new avenues for therapeutic intervention.

Collaborators: 

  • Richard Lock (Children's Cancer Institute, Sydney)

Partners:

  • Child Cancer Research Foundation