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Using demethylating agents to sensitise ependymoma to chemotherapy

Investigators: Raelene Endersby, Keteryne Rodrigues da Silva, Mani Kuchibhotla, Brooke Carline, Nick Gottardo

Project description

Studies have shown that decitabine is a promising drug for the treatment of ependymoma. In this project we aim to test the efficacy of the combination of decitabine with gemcitabine in a very poor prognosis subgroup of ependymoma: ST-EPN-RELA.

Partners

  • The Pirate Ship Foundation