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Showing results for "preterm birth lungs"
Research
The PELICAN (Prematurity's Effect on the Lungs In Children and Adults Network) ERS Clinical Research Collaboration: understanding the impact of preterm birth on lung health throughout lifeAn estimated 15 million babies (∼11%) are born preterm each year (before 37 weeks of gestation), the rates of which are increasing worldwide. Enhanced perinatal care, including antenatal corticosteroids, postnatal surfactant and improved respiratory management, have markedly improved survival outcomes since the 1990s, particularly for babies born very preterm (<32 weeks gestation). However, long-term pulmonary sequelae are frequent in preterm survivors and ongoing clinical management is often required.
The world’s leading preterm scientists and doctors have joined forces to help give babies born very prematurely, the best possible life.
Research
PELICAN: Prematurity’s Effects on the Lungs in Children and Adults NetworkShannon Simpson SS BMedSci (hons), PhD Co-Head, Children's Lung Health; Senior Research Fellow 08 6319 1631 Shannon.simpson@telethonkids.org.au
Research
Antenatal creatine supplementation reduces persistent fetal lung inflammation and oxidative stress in an ovine model of chorioamnionitisChorioamnionitis is a common antecedent of preterm birth and induces inflammation and oxidative stress in the fetal lungs. Reducing inflammation and oxidative stress in the fetal lungs may improve respiratory outcomes in preterm infants. Creatine is an organic acid with known anti-inflammatory and antioxidant properties.
Research
Ventilatory response and stability of oxygen saturation during a hypoxic challenge in very preterm infantsPreterm infants have immature control of breathing and impaired pulmonary gas exchange. We hypothesized that infants with bronchopulmonary dysplasia (BPD) have a blunted ventilatory response and peripheral oxygen saturation (SpO2 ) instability during a hypoxic challenge.
News & Events
Despite advances in neonatal care, preterm babies have lower lung function throughout their lifeAnalysis of worldwide research shows that despite advances in neonatal care, preterm babies have lower lung function throughout their life.
Research
Vitamin A supplementation in very-preterm or very-low-birth-weight infants to prevent morbidity and mortality: A systematic review and meta-Analysis of randomized trialsA previous systematic review showed that intramuscular vitamin A supplementation reduced the risk of bronchopulmonary dysplasia (BPD) in very-low-birth-weight (VLBW) infants. However, more recent studies have questioned this finding.
Research
Preterm Paediatric Inhaled Corticosteroids Intervention (PICSI)Understanding if ongoing inflammation in the lungs contributes to the poor lung health experienced by some children who were born preterm.
News & Events
New risk factor identified to help predict the long-term lung health of young adults born very pretermA study which set out to determine ways to predict the long-term lung health of young adults born very preterm has shown that a childhood history of respiratory hospital admission should be a key consideration in the management of preterm children and adults.
News & Events
Preterm respiratory researchers share what World Prematurity Day means to themPreterm researchers Dr Shannon Simpson (left) and Professor Jane Pillow (right) with Tony Sparks WA chairperson Amber Bates.