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Research

Linking the westernised oropharyngeal microbiome to the immune response in Chinese immigrants

Human microbiota plays a fundamental role in modulating the immune response. Western environment and lifestyle are envisaged to alter the human microbiota with a new microbiome profile established in Chinese immigrants, which fails to prime the immune system. Here, we investigated how differences in composition of oropharyngeal microbiome may contribute to patterns of interaction between the microbiome and immune system in Chinese immigrants living in Australia.

Research

Genome mining and characterisation of a novel transaminase with remote stereoselectivity

Here we report a novel ω-transaminase discovered in a marine sponge Pseudovibrio sp. isolate

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Predicting disease progression in cystic fibrosis

Comprehensive scores incorporating clinical, lung function, imaging and laboratory data will become essential in the future for predicting disease progression and for use in clinical trials

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Navigating 'the system' to find supports and services for people with developmental disability: How can research help make this a better journey?

Parents navigate what can be a confusing world of early intervention services, residing in the health, disability and/or education sectors

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Transition to secondary school: Expectation versus experience

This study investigated what young people in primary school reported being worried about with their impending move to secondary school, and how their...

Research

Is the effect of compulsory community treatment

We investigated whether a reduction of preventable deaths from physical disorders was mediated by better access to specialized medical procedures.

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Chest computed tomography: a validated surrogate endpoint of cystic fibrosis lung disease?

Clinical trials for the treatment of cystic fibrosis (CF) lung disease are important to test and optimise new therapeutic interventions.

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Evaluating a community-based early childhood education and development program in Indonesia: study protocol for a pragmatic cluster randomized controlled trial

The aim of the trial is to evaluate a community-based early education and development program launched by the Government of Indonesia.

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A national prospective surveillance study of acute rheumatic fever in Australian children

Acute rheumatic fever (ARF) is an important cause of heart disease in Indigenous people of northern and central Australia.

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Experience of providing cultural safety in mental health to Aboriginal patients: A grounded theory study

The concept of cultural safety is particularly relevant to mental health professionals as it aims to promote cultural integrity and social justice and equality.