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Wellbeing partnership building resilience after medical trauma

Helping children build resilience and cope with the trauma associated with medical emergencies and chronic health conditions is the focus of a promising pilot program being undertaken by The Kids Research Institute Australia.

Research

Acceptability and Implementation Challenges of Benzathine Penicillin G Secondary Prophylaxis for Rheumatic Heart Disease in Ethiopia: A Qualitative Study

Monthly intramuscular injections of benzathine penicillin G (BPG) remain the cornerstone of secondary prophylaxis for acute rheumatic fever and rheumatic heart disease (RHD). The barriers to successful delivery of BPG may be patient- or service-delivery-dependent.

Research

Antibody responses against influenza A decline with successive years of annual influenza vaccination

Influenza vaccine effectiveness and immunogenicity can be compromised with repeated vaccination. We assessed immunological markers in a cohort of healthcare workers (HCW) from six public hospitals around Australia during 2020-2021.

Research

The relationship between non-communicable disease risk and mental wellbeing in adolescence: a cross-sectional study utilising objective measures in Indonesia

Risk factors for non-communicable diseases (NCDs, cardiovascular diseases, cancers, chronic respiratory diseases, diabetes, and mental disorders) arise in adolescence but are mostly framed as relevant to health in adulthood; little is known about the relationship between co-occurring NCD risks and mental wellbeing in young people.

Research

Identifying SETBP1 haploinsufficiency molecular pathways to improve patient diagnosis using induced pluripotent stem cells and neural disease modelling

SETBP1 Haploinsufficiency Disorder (SETBD) is characterised by mild to moderate intellectual disability, speech and language impairment, mild motor developmental delay, behavioural issues, hypotonia, mild facial dysmorphisms, and vision impairment. Despite a clear link between SETBP1 mutations and neurodevelopmental disorders the precise role of SETBP1 in neural development remains elusive.

Research

Risk factors for diagnosis and treatment delay among patients with multidrug-resistant tuberculosis in Hunan Province, China

Multidrug-resistant tuberculosis (MDR-TB) is a global health threat associated with high morbidity and mortality rates. Diagnosis and treatment delays are associated with poor treatment outcomes in patients with MDR-TB. However, the risk factors associated with these delays are not robustly investigated, particularly in high TB burden countries such as China.

Research

State transitions across the Strep A disease spectrum: scoping review and evidence gaps

The spectrum of diseases caused by Streptococcus pyogenes (Strep A) ranges from superficial to serious life-threatening invasive infections. We conducted a scoping review of published articles between 1980 and 2021 to synthesize evidence of state transitions across the Strep A disease spectrum. We identified 175 articles reporting 262 distinct observations of Strep A disease state transitions.

Research

Trauma-informed prevention programmes for depression, anxiety, and substance use among young people: protocol for a mixed-methods systematic review

Mental ill-health and substance use bear a substantial burden and harm on young people and often arise from co-occurring and compounding risk factors, such as traumatic stress. Trauma-informed prevention of mental ill-health and substance use demonstrates significant promise in reducing this burden.

Research

Geldanamycin treatment does not result in anti-cancer activity in a preclinical model of orthotopic mesothelioma

Mesothelioma is characterised by its aggressive invasive behaviour, affecting the surrounding tissues of the pleura or peritoneum. We compared an invasive pleural model with a non-invasive subcutaneous model of mesothelioma and performed transcriptomic analyses on the tumour samples.

Research

Language, cognitive flexibility, and explicit false belief understanding: Longitudinal analysis in typical development and Specific Language Impairment

The hypothesis that language plays a role in theory-of-mind (ToM) development is supported by a number of lines of evidence.

Dr Mary Abraham wins national diabetes research award

Congratulations to Dr Mary Abraham from the Rio Tinto Children's Diabetes Centre and Perth Children's Hospital, who has been awarded the prestigious Australian Diabetes Society (ADS) Lindsey Baudinet Rising Star Award in T1D Research.

News & Events

Mum wears pump to support daughter's diabetes journey

“I sometimes wish I wasn’t the only one in my family with type 1.” It was this simple statement that prompted mum Candice to walk in her six-year-old daughter Mia’s shoes to attempt to discover what life is like living with type 1 diabetes.

News & Events

Have you got a copy of the new patient folder?

We recently launched our new and improved Children’s Diabetes Centre patient folder so don’t forget to ask for your own hard copy next time you visit the diabetes clinic at Perth Children’s Hospital.

News & Events

Best practice in diabetes care

Last month, our Centre's co-Director Liz Davis, attended the National Association of Diabetes Centre's (NADC) Symposium in Sydney.

News & Events

Our country kids are doing well

Research has shown that no matter where our patients reside in WA, whether it be remote or metropolitan based, the ongoing management of diabetes is the same.