Search
Research
Early life predictors of obstructive sleep apnoea in young adults: Insights from a longitudinal community cohort (Raine study)Obstructive sleep apnea (OSA) increases the risk of perioperative adverse events in children. While polysomnography (PSG) remains the reference standard for OSA diagnosis, oximetry is a valuable screening tool. The traditional practice is the manual analysis of desaturation clusters derived from a tabletop device using the McGill oximetry score. However, automated analysis of wearable oximetry data can be an alternative. This study investigated the accuracy of wrist-worn oximetry with automated analysis as a preoperative OSA screening tool.
Research
The potential global cost-effectiveness of prospective Strep A vaccines and associated implementation effortsGroup A Streptococcus causes a wide range of diseases from relatively mild infections including pharyngitis to more severe illnesses such as invasive diseases and rheumatic heart disease (RHD). Our aim is to estimate the cost-effectiveness of a hypothetical Strep A vaccine on multiple disease manifestations at the global-level.
Research
The diabetes management experiences questionnaire: Psychometric validation among adults with type 1 diabetesTo examine the psychometric properties of the Diabetes Management Experiences Questionnaire (DME-Q). Adapted from the validated Glucose Monitoring Experiences Questionnaire, the DME-Q captures satisfaction with diabetes management irrespective of treatment modalities.
Research
Transient naive reprogramming corrects hiPS cells functionally and epigeneticallyCells undergo a major epigenome reconfiguration when reprogrammed to human induced pluripotent stem cells (hiPS cells). However, the epigenomes of hiPS cells and human embryonic stem (hES) cells differ significantly, which affects hiPS cell function. These differences include epigenetic memory and aberrations that emerge during reprogramming, for which the mechanisms remain unknown.
Research
Psychosocial and neurocognitive correlates of suicidal thoughts and behaviours amongst siblings of persons with and without neurodevelopmental conditionsSiblings of individuals with neurodevelopmental conditions (NDCs) have greater incidence of neuropsychiatric diagnoses and neurocognitive difficulties compared to siblings of persons without NDCs. Despite suicidality being labelled a global health crisis (WHO, 2014) and NDC siblings experiencing risk factors implicated in suicidality, no previous studies examined suicidality amongst adolescent and young adult siblings of persons with NDCs. Our study aimed to bridge this gap.
News & Events
Insulin pumps give better glycaemia outcomes for children than MDIChildren with type 1 diabetes using an insulin pump have better glycaemic control than to those using multiple daily injections (MDI) of insulin, a new Children's Diabetes Centre study has found.
Research
Prevalence and characteristics of paediatric X-linked hypophosphataemia in Australia and New Zealand: Results from the Australian and the New Zealand Paediatric Surveillance Units surveyX-linked hypophosphataemia (XLH) is the most common heritable form of rickets. Prevalence data varies across the literature between 1 in 20,000 and 1 in 200,000 per population.
Research
The epidemiology of superficial Streptococcal A (impetigo and pharyngitis) infections in Australia: A systematic reviewStreptoccocal A (Strep A, GAS) infections in Australia are responsible for significant morbidity and mortality through both invasive (iGAS) and post-streptococcal (postGAS) diseases as well as preceding superficial (sGAS) skin and throat infection. The burden of iGAS and postGAS are addressed in some jurisdictions by mandatory notification systems; in contrast, the burden of preceding sGAS has no reporting structure, and is less well defined.
Research
A Review of Cardiac Surgical Procedures and Their Outcomes for Paediatric Rheumatic Heart Disease in Western AustraliaSurgical intervention is an important treatment modality for advanced rheumatic heart disease (RHD). This study aimed to describe patient characteristics and outcomes from cardiac surgery for RHD in patients referred to the only tertiary paediatric hospital in Western Australia.
News & Events
Would you like to have a mentor?Are you a parent of a child with Type 1 Diabetes who could benefit from having a mentor.... someone who knows what you are going through?
News & Events
Diabetes clinic: We've movedWith a little over a week before outpatient clinics move from Princess Margaret Hospital (PMH) to Perth Children’s Hospital (PCH), now is the time to familiarise yourself with all the information you need to know before you make your first visit.
News & Events
Does your school pass the test?Do you feel your child is well supported by their school when it comes to managing diabetes? If so, our researchers want to hear from you.
News & Events
Tips for a good clinic visitThe Diabetes Service at Perth Children’s Hospital cares for approximately 1000 children with diabetes. Read these tips to ensure you have a good visit.
News & Events
Ten Day Continuous Glucose Monitoring study – now recruitingThe Children’s Diabetes Centre is now recruiting for a new continuous glucose monitoring study.
News & Events
Camp volunteers neededDiabetes WA is looking for volunteers to take part in the PMH and Diabetes WA Camp for 9 and 10 year olds in Hillarys in September.
News & Events
Farewell TariniAfter nearly two-and-a-half years in sunny Perth, Dr Tarini Chetty is headed back home to Scotland. Before she departs our shores.
News & Events
ENDIA milestoneThe ENDIA study — Australia’s largest study into the causes of Type 1 Diabetes— reached a significant milestone when it recruited its 700th patient in Perth.
The Rio Tinto Children’s Diabetes Centre; a Breakthrough T1D Centre of Excellence at The Kids Research Institute Australia and Perth Children’s Hospital (PCH), is a global hub for research into type 1 diabetes (T1D) in children.