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Research
Development of a pharmaceutical science systematic review process using a semi-automated machine learning tool: Intravenous drug compatibility in the neonatal intensive care settingOur objective was to establish and test a machine learning-based screening process that would be applicable to systematic reviews in pharmaceutical sciences. We used the SPIDER (Sample, Phenomenon of Interest, Design, Evaluation, Research type) model, a broad search strategy, and a machine learning tool (Research Screener) to identify relevant references related to y-site compatibility of 95 intravenous drugs used in neonatal intensive care settings.
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The challenge of enteric feverEnteric fever prevention requires significant long term investment in provision of clean water and sanitation; vaccination offers medium term control.
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High tidal volume ventilation does not exacerbate acid-induced lung injury in infant ratsThe impact of mechanical ventilation with high VT-low PEEP in infant rats with preinjured lungs is unknown.
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Research
Epigenetics of the non-coding RNA nc886 across blood, adipose tissue and skeletal muscle in offspring exposed to diabetes in pregnancyDiabetes in pregnancy is associated with increased risk of long-term metabolic disease in the offspring, potentially mediated by in utero epigenetic variation. Previously, we identified multiple differentially methylated single CpG sites in offspring of women with gestational diabetes mellitus, but whether stretches of differentially methylated regions can also be identified in adolescent GDM offspring is unknown.
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S. aureus colonization in healthy Australian adults receiving an investigational S. aureus 3-antigen vaccineBased on descriptive analyses of this small study, S. aureus 3-antigen vaccine vaccination did not impact S. aureus acquisition or carriage
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Outcome measures for artificial pancreas clinical trials: A consensus reportResearch on and commercial development of the artificial pancreas (AP) continue to progress rapidly, and the AP promises to become a part of clinical care.
News & Events
Clinic news December 2021Stay updated with the latest news and events from Clinikids in December 2021, focusing on child health innovations and community engagement. Explore more now!