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Research

Efficacy of the MiniMed™ 670G hybrid closed loop system in managing postprandial glucose excursion with high protein high fat foods in children and adolescents under free-living conditions

High protein high fat meals are considered “difficult” foods because they can cause prolonged hyperglycemia after ingestion. The potential of hybrid closed loop therapy in managing postprandial glucose excursions with these difficult foods remains unknown. This pilot study aimed to explore the impact of manual mode in standard insulin pump therapy and auto mode with hybrid closed loop pump therapy in managing glucose excursions caused by HPHF foods and to obtain feedback from families about each mode.

Research

Epidemiology of intussusception before and after rotavirus vaccine introduction in Fiji

The incidence of intussusception pre-rotavirus vaccine in Fiji is low

Research

Phylomer Libraries: A Rich Source of Peptide Hits in Phenotypic and Target Directed Screens

The poor hit rates associated with conventional random peptide libraries present formidable challenges in genetic screening formats with limited throughput.

Research

Focused transcription from the human CR2/CD21 core promoter is regulated by synergistic activity of TATA and Initiator elements in mature B cells

Mature B cells, CR2/CD21 transcription proceeds from a focused TSS regulated by a non-consensus TATA box, an initiator element and downstream promoter element

Research

Language, cognitive flexibility, and explicit false belief understanding: Longitudinal analysis in typical development and Specific Language Impairment

The hypothesis that language plays a role in theory-of-mind (ToM) development is supported by a number of lines of evidence.

News & Events

Clinic update - December 2023

There is lots of news to report from the clinic including holiday shutdown dates, appointment scheduling, staff updates, changes to creche, and service availability.

Landmark study heralds new era for diabetes management

One hundred years after the discovery of insulin, technology advancements are being heralded as the dawn of a new era for managing type 1 diabetes (T1D) in young people.

Gold standard treatment for all diabetes patients

Imagine you had a healthy daughter one day and the next being told she has an incurable condition that requires day-to-day care and insulin treatment to stay alive.

Research

Early lung surveillance of cystic fibrosis: what have we learnt?

Newborn screening (NBS) for cystic fibrosis (CF) provides an opportunity to commence management and therapeutic interventions significantly earlier

Research

Updates in infant acute lymphoblastic leukemia and the potential for targeted therapy

Outcomes for infants diagnosed under 1 year of age with KMT2A-rearranged acute lymphoblastic leukemia (ALL) have remained stagnant over the past 20 years. Successive treatment protocols have previously focused on intensification of conventional chemotherapy, but increased treatment-related toxicity and chemoresistance have led to a plateau in survival.