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Pulmonary diffusing capacity in healthy Caucasian childrenPrevious studies of pulmonary diffusing capacity in children differed greatly in methodologies; numbers of subjects evaluated, and were performed prior to...
Research
Fusionfinder: A software tool to identify expressed gene fusion candidates from RNA-seq dataThe hallmarks of many haematological malignancies and solid tumours are chromosomal translocations, which may lead to gene fusions.
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TLR3 and RIG-I gene variants: Associations with functional effects on receptor expression and responses to measles viruMeasles virus causes severe morbidity and mortality, despite the availability of measles vaccines. Successful defence against viral pathogens requires early...
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Parental occupational exposure to engine exhausts and childhood brain tumorsChildhood brain tumors (CBT) are the leading cause of cancer death in children; their risk factors are still largely unknown.
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Increased mortality among Indigenous persons during and after release from prison in New South WalesThe objective of this study was to estimate the overall and cause specific mortality of Aboriginal offenders in New South Wales (NSW), Australia.
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Progression of early structural lung disease in young children with cystic fibrosis assessed using CTCross-sectional studies implicate neutrophilic inflammation and pulmonary infection as risk factors for early structural lung disease in infants and young...
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Small macrophages are present in early childhood respiratory diseaseRecently, an established "small macrophage" phenotype has been observed in the sputum of patients with CF and COPD. However, little is known about the...
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Efficacy of acute myeloid leukemia therapy without stem-cell transplantation in a child with blastic plasmacytoid dendritic cell neoplasmOur case demonstrates that AML therapy, without HSCT, can be sufficient to treat this rare disease in children.
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Genetic and functional evidence for a locus controlling otitis media at chromosome 10q26.3Otitis media (OM) is a common childhood disease characterised by middle ear effusion and inflammation.
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Gaps in Indigenous disadvantage not closing: A census cohort study of social determinants of health in Australia, Canada, and New Zealand from 1981-2006Australia, Canada, and New Zealand are all developed nations that are home to Indigenous populations which have historically faced poorer outcomes than their...