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Research

Significant global variation exists in neonatal nutrition practice, including in assigned milk composition values, donor milk usage, fortification regimens, probiotic choice and in methods used to calculate and report nutrition and growth outcomes, making it difficult to synthesize data to inform evidence-based, standardized nutritional care that has potential to improve neonatal outcomes

Research

Rural/remote blood collection can cause delays in processing, reducing PBMC number, viability, cell composition and function. To mitigate these impacts, blood was stored at 4◦ C prior to processing. Viable cell number, viability, immune phenotype, and Interferon-γ (IFN-γ) release were measured.

Research

Medulloblastoma (MB) consists of four core molecular subgroups with distinct clinical features and prognoses. Treatment consists of surgery, followed by radiotherapy and cytotoxic chemotherapy. Despite this intensive approach, outcome remains dismal for patients with certain subtypes of MB, namely, MYC-amplified Group 3 and TP53-mutated SHH. Using high-throughput assays, six human MB cell lines were screened against a library of 3208 unique compounds. We identified 45 effective compounds from the screen and found that cell cycle checkpoint kinase (CHK1/2) inhibition synergistically enhanced the cytotoxic activity of clinically used chemotherapeutics cyclophosphamide, cisplatin, and gemcitabine.

Research

A non-progressive motor disability due to damage of the developing brain, this is the most common physical disability in childhood. Affecting about one in 500 babies, it is frequently accompanied by other neurological impairments, such as intellectual or sensory.

The first ever National Healthy Skin Guideline has become the gold standard for the treatment, prevention and public health control of skin infections in Indigenous populations in Australia and provides a positive framework for healthy skin.

Engaging the community in COVID-19 rapid research

The research that is reducing the impact on families done by The Kids Research Institute Australia.

Infographics to easily learn more about bullying and what actions to take should bullying be an issue in your school or community.

Research

Glue ear is when a child's middle ear fills with sticky fluid behind the ear drum. A common condition, glue ear usually goes undetected, as it's not an obvious condition from the outside.

Research

In Vitro Fertilisation (IVF) is an Assisted Reproductive Technology (ART) in which an egg is fertilised by sperm outside the body.