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Research
Changes in the FEV/FVC ratio during childhood and adolescence: an intercontinental studyIn children, the ratio of forced expiratory volume in 1 s (FEV₁) to forced vital capacity (FVC) is reportedly constant or falls linearly with age...
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Respiratory allergen from house dust mite is present in human milk and primes for allergic sensitization in a mouse model of asthmaThese data highlight that antigen administration to the neonate through the oral route may contribute to child allergic sensitization and have important...
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Levels of innate immune factors in preterm and term mothers' breast milk during the 1st month postpartumPreterm breast milk contains significantly higher concentrations of some immune proteins than term breast milk
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Understanding the implementation of health checks in the prevention and early detection of chronic diseases among Aboriginal and Torres Strait Islander people in Australia: a realist review protocolChronic disease remains the leading cause of morbidity and mortality among Aboriginal and Torres Strait Islander peoples in Australia. Regular structured, comprehensive health assessments are available to Aboriginal and Torres Strait Islander people as annual health checks funded through the Medicare Benefits Schedule.
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Effectiveness of rotavirus vaccines in an Australian population: A case-control studyRV1 and RV5 were both effective in preventing laboratory confirmed and notified rotavirus infections among children aged <5 years
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Antibody and cell-mediated immunity to pertussis 4 years after monovalent acellular pertussis vaccine at birthIn the longest reported follow-up of infants who received aP vaccine at birth, we found a trend to lower PT IgG antibodies post booster compared with receipt...
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Birth cohorts in asthma and allergic diseases: Report of a NIAID/NHLBI/MeDALL joint workshopPopulation-based birth cohorts on asthma and allergies increasingly provide new insights into the development and natural history of the diseases.
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Severe winter asthma exacerbations can be prevented by omalizumab, but there is no carryover effect.Recurrent severe asthma exacerbations are associated with decreased lung growth or accelerated loss of long function and add substantially to cost and morbidity
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Diet at birth is critical for healthy growth, independent of effects on the gut microbiotaColostrum is the first milk for a newborn. Its high content in microbiota shaping compounds and its intake at the time of gut microbiota seeding suggests colostrum may be critical in the establishment of a healthy microbiota. There is also accumulating evidence on the importance of the gut microbiota for healthy growth.
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The Western Environment Reduces Innate Immune Cytokine Production in Chinese ImmigrantsWe recruited age- and sex-matched Chinese immigrants living in Western Australia for less than 6 months (newly arrived, n = 22) or more than 5 years.