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Vaccine prevention of GAS infections and their immunological complications has been a goal of researchers for decades.

The desire for an effective vaccine arises from the large burden of disease caused by the bacterium, particularly rheumatic fever and rheumatic heart disease.

Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) occur at very high rates among Aboriginal and Torres Strait Islander people.

We review GAS transmission characteristics and prevention strategies, historical and geographical trends and report on the estimated global burden disease...

Acute rheumatic fever (ARF) is an important cause of heart disease in Indigenous people of northern and central Australia.

In Australia, rheumatic heart disease (RHD) is almost exclusively restricted to Aboriginal Australian and Torres Strait Islander people with children being...

Globally, ARF and RHD cause more than a quarter of a million deaths and substantial disability each year.

End RHD CRE News & Events

Across Australia, more than 5,000 Aboriginal and Torres Strait Islander people are currently living with rheumatic heart disease (RHD) or its precursor, acute rheumatic fever (ARF).

For Aboriginal Community Researchers Minitja Marawili and Yunutju Gondarra, the work of the END RHD CRE is deeply personal.